8. 45 Points in Game 7 of Eastern Conference Semifinals
On May 18, 2008, against the Boston Celtics, the Cavaliers come up short 97-92, despite 45 points from James. The Cavaliers were unable to stop Paul Pierce who tossed in 41 on the afternoon. James’ aggressive play saw him go to the free throw line 19 times in the game, converting on 14 of those opportunities.